Colorado's Seed-Stage Venture Capital Fund


Leading Seed Investment Rounds

The Innosphere Fund was formed to accelerate the growth and exit of Innosphere’s client companies.

The Fund seeks to lead seed-stage investment rounds in companies with motivated founders that are likely to achieve a near-term exit through a corporate acquisition, and require smaller amounts of capital to achieve superior growth milestones. 

Innosphere Fund: Accelerating the path to a successful exit

  • Seed-stage venture capital fund
  • Innosphere is a General Partner of the Fund
  • Available only to Innosphere Client Companies 

Innosphere is Colorado’s leading technology incubator for startup and scaleup companies in the industries of enterprise software, IoT, hardware, bioscience, health innovation, medical device, cleantech, energy, and advanced materials. 

Innosphere partners with the leading research universities in the state including: University of Colorado, Colorado School of Mines, and Colorado State University, which creates further differentiated deal flow for the Fund.

Companies in the incubation program are supported by former C-level executives, experienced staff, and industry-specific advisors to support the company in becoming investor-ready.

The Fund's Unique Approach

Proprietary Deal Flow

Positioned to invest in the best high-tech companies in Colorado.

Focused on Early Exits

A consistent process for supporting early exit returns for Limited Partners.

Active Management

A limited portfolio to ensure active support for companies with board representation.

Our Portfolio

Incident Response Technologies, Inc.


Incident Response Technologies, Inc. (IRT) is a Denver-based startup company providing cloud-based solutions for public safety organizations since 2005. IRT's flagship product, the Rhodium Incident Management Suite, is currently in use throughout the United States and Canada by Police, Fire, EMS, Emergency Management, Campus Security, and other organizations.

Press Release: IRT Closes $1.2M Seed Round led by Innosphere Fund

Aspero Medical Corporation


Aspero Medical’s technology was developed at the University of Colorado and has a differentiated medical product for use in endoscopy procedures which results in improved performance, saving time and money, and improved patient outcomes. The company focuses on gastrointestinal (GI) diseases which affect approximately 25% of Americans annually. Physician outcomes are faster procedures, improved patient outcomes, and reduction of multiple procedures for individual patients. 

Press Release: Innosphere Fund invests in University of Colorado medical device startup

Our Portfolio

Catalyze, Inc.


 Catalyze believes that commercial real estate can play a major role in addressing the need for energy storage in distribution systems and on real estate sites. Catalyze is an advanced software and data analytics company that partners with commercial real estate to transform commercial properties into resilient, renewable utilities. Catalyze enables commercial property owners to optimize design and location of anchor buildings for microgrids, which in turn provides them with lower-cost, more reliable electric power.

Press Release: Innosphere Client Company, Catalyze, secures growth financing from Innosphere Fund

Epic River Healthcare, Inc.


 Epic River is a developer of software solutions intended to streamline and accelerate payment processes for healthcare providers, financial institutions and patients. The company provides better loan terms, lower cost of closing and unsurpassed convenience to customers to improve the financial wellbeing of the community in which they live and work, enabling healthcare providers to accelerate cash flow, offload the cost of managing internal payment plans and increase collection success. For more information on the Epic River solution, please visit

Press Release: Epic River Closes $1.75 million in seed round led by Innosphere Fund

Our Team

General Partner: Mike Freeman


Mike Freeman has been the Chief Executive Officer of Innosphere since 2012.  Previously, Mike was Innosphere’s Board Chair for 5 years.  Innosphere is Colorado’s leading non-profit technology incubator which serves more than 40 startup and scaleup companies annually which employ around 250 employees.  

Mike is responsible for all Innosphere operations, finances, strategy and execution. 

Previously, Mike served in several high-level public sector executive roles including City Manager. He has an extensive public power management background, has run several management consulting practices, and serves as a director on many boards. 

Mike is a General Partner of two early-stage venture capital funds: the Innosphere Fund and the Israel-Colorado Innovation Fund.

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General Partner: Mark Newhouse


Mark Newhouse has built his highly successful career delivering breakthrough products and businesses that have generated more than $2.0 billion in revenue, in the telecommunications, consumer electronics and cleantech markets. As part of that work, Mark has directed and negotiated multiple acquisitions of startup companies and the acquisition of key IP assets.

Mark came to Denver from Shanghai where he was a Senior Vice President of Corning Incorporated. Since coming to Colorado Mark has been investing in and advising a variety of startup companies including: Bioptigen (acquired by Danaher in 2016), Replay Technologies (acquired by Intel in 2016), Insight Photonics, Yonomi, Zoomcar, Arbe Robotics, and the Maniv Mobility Fund.

Mark currently serves on the Board of Denver Social Venture Partners, Colorado Pledge 1% and Impact Charitable.

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Principal: Joey Davis


Joey has held a myriad of roles focused on investment and financial analysis. His career began with a position working at Lehman Brothers in New York City. 

Joey also worked for Raymond James, where he spent a year in their management rotational program, including stints in corporate and investment banking, before spending three years with the company’s internal private equity group. Following his time with Raymond James, Joey worked as a consultant partnering with management at private companies to lead financial, operational and strategic projects.

Joey joined the Innosphere Fund in July of 2018. His primary responsibilities for the Fund include leading due diligence, financial analysis, investor relations and pipeline development. Joey earned his Bachelor’s, Master’s and JD from the University of Florida.

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About Innosphere

The Program for Starting and Scaling Science and Technology-Based Companies

Innosphere is a nonprofit 501(c)(3) technology incubator accelerating the success of high-impact science and technology startup and scaleup companies in Colorado. Innosphere’s program focuses on ensuring companies are investor-ready, connecting entrepreneurs with experienced advisors, making introductions to corporate partners, exit planning, and accelerating top line revenue growth. 

If you're a high-growth science or tech company in Colorado you've come to the right place! Once accepted into the program, Innosphere Client Companies receive ongoing support to ensure they’re getting the know-how to raise the right kind of capital and developing all the resources to grow.

Become an Innosphere Client Company

With 20 years of experience, Innosphere’s tested model has supported hundreds of companies in reaching their key milestones.

For information on submitting an application to Innosphere's incubator for science and technology companies, please reach out to Scott Sampl, Innosphere's Chief Operating Officer, at


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Questions? Use this form to directly contact Innosphere Fund General Partner, Mike Freeman.